Alzheimer's test reveals severity

A blood biomarker can reveal the severity of Alzheimer's disease, research suggests.

A team from Erasmus Medical Centre in Rotterdam, the Netherlands, found levels of the protein clusterin were linked to the prevalence and severity of Alzheimer's disease. But it found no link with the development of Alzheimer's, suggesting it is not a useful target for detecting risk.

Researchers analysed baseline plasma levels of clusterin in 60 patients with Alzheimer's disease and a control group of 926 patients. These patients, and a further 156 patients diagnosed with Alzheimer's during the follow-up, were measured again after 7.2 years.

The likelihood of developing Alzheimer's disease increased by 63 per cent for each standard deviation increase in plasma clusterin level.

Visit JAMA for more Alzheimer's articles

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Doctors are being 'taxed out of the NHS', warns BMA chair

Doctors are being 'taxed out of the NHS', warns BMA chair

The NHS risks being brought to a standstill because 'perverse and punitive pension...

Welsh GP contract deal delivers £25m funding boost and partner incentives

Welsh GP contract deal delivers £25m funding boost and partner incentives

GPs in Wales will receive a £25m increase in funding in 2019/20 as part of a new...

Elected BMA members to receive equality training after sexism investigation

Elected BMA members to receive equality training after sexism investigation

BMA chair Dr Chaand Nagpaul has promised that the association will 'learn, act and...

NHS Resolution moves to allay fears over state indemnity 'small print'

NHS Resolution moves to allay fears over state indemnity 'small print'

Information about GPs will only be passed to the GMC under 'very rare circumstances'...

BMA U-turn over sexism and harassment debate at annual conference

BMA U-turn over sexism and harassment debate at annual conference

Doctors' leaders will debate claims that the BMA fails to address sexism and harassment...

Doctors begin giving evidence in BMA sexism investigation

Doctors begin giving evidence in BMA sexism investigation

Doctors have started giving evidence as part of the investigation into sexism and...