Test your knowledge on haematology

Read the article on haematology then answer these three questions to check your understanding. You may want to document your answers and any learning points to save in your CPD folder along with the article.

Read our clinical feature on haematology

Test your knowledge
QUESTION

Are the following statements true or false?

1. G6PD Deficiency does not affect women.


2. Polychromasia, blister cells and Heinz Bodies are a feature of G6PD deficiency.


3. Lead toxicity is due to free radical damage to cell structures and interferes with DNA transcription.


4. Blood film features of a microcytic anaemia with basophilic stippling are consistent with lead toxicity.


5. There is a significant correlation between the distribution of G6OD deficiency and prevalence of Plasmodium falciparum malaria.


6. Clinical manifestation/severity of G6PD deficiency will depend on the degree of enzyme deficiency.


7. Pica syndrome is a recognised manifestation of lead toxicity.


8. Neurological problems can be seen in G6PD deficiency and lead toxicity.

ANSWER

1. False. Females may be affected due to lyonisation. This in uncommon but possible

2. True

3. True

4. True

5. True.  There is an evolutionary protective mechanism of G6PD in malaria endemic areas

6. True. See the WHO classification

7. False. This is associated with severe chronic iron deficiency

8. True


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