Once-a-day GLP-1 controls glucose

American Diabetes Association Conference - Novel way to control glucose

The GLP-1 analogue liraglutide can improve blood glucose control when given once a day, a study has shown.The drug is currently in development and is expected to be launched later this year.

In the latest study, nearly 500 patients with inadequately controlled type-2 diabetes, who were taking metformin with or without a sulfonylurea, were given liraglutide or the twice- daily GLP-1 analogue exenatide and monitored for change in HbA1c.

Liraglutide reduced the mean HbA1c by 1.12 per cent compared with a reduction of 0.79 per cent for patients on exenatide.

More patients achieved an HbA1c level of less than 7 per cent in the liraglutide group than in the exenatide group.

Professor Stephen Gough, professor of medicine and honorary consultant physician at the University of Birmingham said he thought the drug would be suitable for use after metformin for most type-2 diabetes patients.

The findings were presented at the American Diabetes Association meeting in New Orleans this week.

emma.quigley@haymarket.com

Comment below and tell us what you think

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Before commenting please read our rules for commenting on articles.

If you see a comment you find offensive, you can flag it as inappropriate. In the top right-hand corner of an individual comment, you will see 'flag as inappropriate'. Clicking this prompts us to review the comment. For further information see our rules for commenting on articles.

comments powered by Disqus