New insulins could cut injections needed

New insulins under development could slash the number of injections people with diabetes have to take.

New insulins will last longer
New insulins will last longer

These longer-acting basal insulins may only need to be injected twice a week, rather than once or twice daily.

If late-stage human trials currently underway are successful, these second-generation analogue insulins could be on the market in the next three years.

Novo Nordisk is developing two such products, which it describes as ‘ultra long acting new generation' insulins.

One has a very ‘flat' profile - maintaining a steady effect over a long period - and is being tested for use three times a week. Another includes a boost of bolus insulin and is designed to be injected at meal times.

Both are being tested for type-1 diabetes in combination with rapid-acting analogues and for type-2 diabetes on their own and in combination with metformin and pioglitazone.

Head-to-head trials are also comparing these longer-acting analogues with biphasic insulins and long-acting analogue insulins.

These second-generation products have been designed to improve the way that insulin is delivered to the liver and thereby produce a flatter action profile.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Before commenting please read our rules for commenting on articles.

If you see a comment you find offensive, you can flag it as inappropriate. In the top right-hand corner of an individual comment, you will see 'flag as inappropriate'. Clicking this prompts us to review the comment. For further information see our rules for commenting on articles.

comments powered by Disqus