MIMS Summary: NICE approves adalimumab for psoriasis

NICE has published guidance on the use of adalimumab (Humira), an anti-TNF agent for the treatment of psoriasis.

It recommends adalimumab as a treatment option for adults with plaque psoriasis for whom anti-TNF treatment is being considered and when both of the following criteria are fulfilled:

  • The disease is severe (defined as a Psoriasis Area Sensitivity Index [PASI] and a Dermatology Life Quality Index [DLQI] of more than 10).
  • The disease has not responded to previous therapies including ciclosporin, methotrexate and PUVA, or the patient is intolerant or has a contraindication to these treatments.
  • Adalimumab should be discontinued in patients whose psoriasis has not responded adequately at 16 weeks.

Read the full NICE guidance

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