Kidney mortality greater for men

Women with chronic kidney disease (CKD) survive longer, are less likely to suffer kidney failure and experience a slower decline in glomerular filtration rate (GFR) than men with the condition, a Norwegian study has found.

Researchers identified 928 men and 2,119 women in the early stage of CKD and monitored their GFR readings, renal survival and mortality over a 10-year period to identify gender differences in the prognosis of the disease.

Women were found to have a slower decline in GFR than men, who had more serious outcomes.

The 10-year mortality rate in men was over 60 per cent compared to 47 per cent in women, and the men's risk of renal failure over 10 years was more than double the risk in women.

The authors of the study said that for most CKD patients the risk of CVD outweighs that of renal failure.

They added that their results supported modifying guidelines to take into account gender differences in care needs for CKD.

They concluded that preventative measures could be important in men with the condition.

Kidney International 2006; 69: 375-82.

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