Among the changes, the government said it has introduced new safeguards against price competition, privatisation and private companies ‘cherry-picking’ profitable NHS business.
The government has also confirmed patients will continue to have the legal right to drugs and treatments that have been recommended by the NICE beyond 2014 and the introduction of value-based pricing.
The government said the ‘substantial changes’ it will make will ‘strengthen’ its plans in the interests of patient.
But it said despite the amendments, it remains true to the core principles of the reforms, including ensuring the NHS is led by front line clinicians.
Health Secretary Andrew Lansley said: ‘It was right that we took the time to pause, listen, reflect and improve our plans and I believe our proposals are now stronger thanks to this process.
‘I believe the revised plans we set out today will both safeguard the future of our NHS, and ensure it is more efficient and more accountable, moving us closer to having a high-quality health service that puts patients at the heart of everything it does.’