Evidence base: Cushing's syndrome

A summary of the evidence behind the diagnosis and management of Cushing's syndrome

Stretch marks caused by Cushing's syndrome (Photograph: SPL)
Stretch marks caused by Cushing's syndrome (Photograph: SPL)

Clinical trials

  • Valassi E, Santos A, Yaneva M et al; ERCUSYN Study Group. The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics. Eur J Endocrinol 2011; 165(3): 383-92.
  • Clayton RN, Raskauskiene D, Reulen RC et al. Mortality and morbidity in Cushing's disease over 50 years in Stoke-on-Trent, UK: audit and meta-analysis of literature. J Clin Endocrinol Metab 2011; 96(3): 632-42.
    Page 163: ABLE 4. Summary of all studies reporting mortality in CD.
  • Guignat L, Bertherat J. The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline: commentary from a European perspective. Eur J Endocrinol 2010; 163(1): 9-13.
    Page 163: Table 1. Diagnosis of Cushing's syndrome: who should be investigated?
    Page 164: Table 2. How to investigate for Cushing's syndrome.

Guidelines

  • Nieman LK, Biller BM, Findling JW et al. The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2008; 93(5): 1526-40.
    Page 1,528: Table 1. Overlapping conditions and clinical features of Cushing's syndrome.
    Page 1,531: Figure 1. Algorithm for testing patients suspected of having Cushing's syndrome.
  • Biller BM, Grossman AB, Stewart PM et al. Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab 2008; 93(7): 2454-62.
    Page 2,455: Criteria for Cure and Remission of ACTH-Dependent Cushing's Syndrome.
  •  By Dr Krystallenia Alexandraki, consultant endocrinologist, Barts and The London NHS Trust, and Professor Ashley Grossman, professor of endocrinology, Oxford Centre for Diabetes, Endocrinology and Metabolism.

 

 

 

 

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