Exclusive: One in five dementia scrips for anti-psychotics
04 June 2009
One in five UK prescriptions for dementia drugs are still for anti-psychotic treatments, which may be inappropriate, and the use of effective Alzheimer's treatments are among the lowest in Europe, GP newspaper can exclusively reveal.
The DoH will publish its long-awaited review of the use of anti-psychotics in dementia this month, following months of delay. But a review conducted by IMS for the Alzheimer’s Society found that the drugs are still widely used in dementia care. Some 20% of all prescriptions for dementia in the year to October 2008 were for anti-psychotic drugs.
Prescribing for anti-psychotics varied across England, with 21% of dementia patients in the North West receiving the drugs, compared with 14% of those in the South West.
The review also found that the use of cholinesterase inhibitors, such as donepezil, rivastigmine and galantamine, varied by almost 70% regionally. Overall, prescribing of these drugs was well below other European countries such as Spain, Sweden and Germany. NICE has restricted the use of cholinesterase inhibitors to only those patients with moderate disease severity.
Professor Steve Iliffe, professor of primary care for older people at University College London said: ‘The UK is probably under-prescribing anti-Alzheimer’s drugs because PCTs are using the NICE guidance to restrict the use of the drugs.’
Professor Clive Ballard, director of research at the Alzheimer’s Society, said that anti-psychotic prescribing remained ‘inappropriately high’ and should only be used to treat severe symptoms or in exceptional circumstances and for short periods. He said that the problem lies partly in the fact that GPs are not well supported by other local services. He added that PCTs needed to commission services such as local rapid response teams that include psychologists.
Neil Hunt, chief executive of the Alzheimer’s Society, added: ‘Anti-psychotics can double risk of death, triple risk of stroke and accelerate symptoms in people with dementia. It is absolutely disgraceful that so many people across the UK are inappropriate prescribed these drugs.
‘Anti-psychotics should only be used to treat severe symptoms in exceptional circumstances and only for short periods. Specialist dementia training vastly increases quality of life and could save the UK £35m a year if it was mandatory. The government must address this serious issue and publish its long awaited review.’
A previous investigation by GP newspaper in October 2008 found that one in four PCTs had closed or reduced dementia services in the previous three years and less than half had early detection services in place.
sanjay.tanday@haymarket.com
- For the full version of this story read this week’s GP dated 5 June.
- For the full report contact Peter Stephens at IMS. pstephens@uk.imshealth.com
Comment below and tell us what you think
Additional Information

Latest jobs Jobs web feed
- Salaried/Lead GPs Malling Health Competitive, role dependant, NHS Pension and defence fees reimbursed, Nationwide
- Salaried GP The Practice plc £75-85k FTE +NHS pension, Ely or Leicester
- Regional Clinical Leads The Practice plc Salary £95-105k FTE + NHS pension, Leicester or Sheffield
- Salaried GP St Peter's Hill Surgery Competitive, Grantham, Lincolnshire
- GP Locum - Cambridgeshire - March, Kings Lynn, Peterborough Agenda Medical Locums up to £650.00 per day, March, Cambridgeshire, South East England
- Salaried Single Handed GP, Kent, 8-9 Sessions per week + PDP, up to £90k + NHS Pension + MDU + PDP Global Medics Permanent UK Salary up to £90k for up to 9 sessions + NHS Pension + MDU + PDP, South East England, Kent
Most read
- Health secretary says GPs have 'ethical duty' to save NHS costs
- NHS Commissioning Board chairman rebuked for 'golf-playing GPs' jibe
- Government department sessions (where BMA 'Treasury rate' is accepted)
- GPs face 'outcomes targets overload', patient group warns
- DH could face legal challenge over risk register veto
- NICE to develop multimorbidity guidelines for GPs
Most commented
MIMS Drug Search
Possible searches include drugs (by brand, generic ingredient or drug class), diseases and more.







