Aspirin boost to colon cancer test
10 December 2010
Low-dose aspirin may improve the performance of tests for colorectal cancer, a study suggests.
German researchers looked at the issue because screening for colorectal cancer is often carried out in populations in whom use of low-dose aspirin is common.
Low-dose aspirin increases the risk of gastrointestinal bleeding and so concerns have been raised that it may affect the specificity of tests for colorectal cancer.
Dr Hermann Brenner and colleagues from the German Cancer Research Centre in Heidelberg assessed the performance of immunochemical faecal occult blood tests in around 4,000 people.
They found that the use of low-dose aspirin was associated with a markedly higher sensitivity for detecting advanced colorectal neoplasms, with only a slightly lower specificity.
The researchers said the possibility that test performance may be enhanced by temporary use of low-dose aspirin will need to be followed up in large randomised studies.
- Related MIMS Guidelines and Summaries
- Bevacizumab in Combination With Gemcitabine and Carboplatin for Treating the First Recurrence of Platinum-Sensitive Advanced Ovarian Cancer (TA285)
- Bevacizumab in Combination with Paclitaxel and Carboplatin for First-Line Treatment of Advanced Ovarian Cancer (TA284)
- Vinflunine for the Treatment of Advanced or Metastatic Transitional Cell Carcinoma of the Urothelial Tract (TA272)
Send to a friend
Latest jobs Jobs web feed
- Salaried GP The Higham Ferrers Surgery Salary negotiable , Higham Ferrers, Northamptonshire
- Full Time Salaried GP Daneshouse Medical Centre Salary dependant on qualifications and experience, Burnley, Lancashire
- Salaried GP The Elms Medical Centre Negotiable depending upon experience, newly qualified starting at circa £72k pro-rata., North West England
- SALARIED GP (female) Mount Pleasant and Earlsheaton Medical Centres Dependent upon experience, Dewsbury / Batley, West Yorkshire
- Full Time GP Partner/ Salaried GP Newtown Medical Practice Negotiable, Mid Wales/Shropshire Border
- Salaried GP's Avicenna Medical Practice Negotiable and to include benefits, Bradford, West Yorkshire
- Hunt to reveal GP reforms and new inspection regime
- LMCs demand emergency vote after Hunt out-of-hours comments
- Integrated care pilot drives up dementia diagnosis
- Hunt 'must recognise growing GP crisis', warns RCGP
- GP contract 'not to blame' for A&E pressure, NHS leaders say
- GP-patient relationship faces 'unprecedented strain'
MIMS Drug Search
Possible searches include drugs (by brand, generic ingredient or drug class), diseases and more.